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HealthSprit

HealthSprit
Mechanisms, evidence and safety

Pharmacology

Explore hormones, medicines and investigational compounds with attention to mechanisms, the quality of evidence and possible adverse effects.

Pharmacology / 7 min

Testosterone enanthate and cardiovascular health

How testosterone enanthate affects cholesterol, blood pressure and hematocrit, and why cardiovascular risk must be assessed in context.

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Pharmacology / 7 min

Trenbolone acetate: history and medical use

From laboratory development to veterinary implants: the history of trenbolone acetate and its distinction from historical human formulations.

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Pharmacology / 7 min

Methandienone side effects: an overview of risks

A structured overview of methandienone risks involving the liver, cardiovascular system, hormone production, fertility, skin and mental health.

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Pharmacology / 8 min

Methenolone acetate: receptors and protein synthesis

How methenolone interacts with androgen receptors, influences gene transcription and differs from testosterone in metabolism and activity.

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Pharmacology / 7 min

Tesamorelin: WADA classification and legal status

Understand tesamorelin’s anti-doping classification, the distinction between medical approval and sport rules, and therapeutic use exemptions.

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Pharmacology / 7 min

Insulin: its mechanism and effects on the body

Insulin signalling explained: glucose transport, glycogen storage, protein metabolism, potassium balance and the development of insulin resistance.

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Pharmacology / 7 min

Semaglutide in sport: expectations and reality

Appetite control, body composition and energy availability: why expectations about semaglutide in sport must be compared with clinical evidence.

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Pharmacology / 5 min

Finasteride: contraindications and interactions

Key contraindications, pregnancy-related handling precautions, potential interactions and clinical considerations associated with finasteride.

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Pharmacology / 7 min

S23 and the liver: what is known about risk

What can and cannot be inferred about S23 liver risks from research on SARMs, reported injury patterns and the uncertainty of unregulated products.

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Pharmacology / 8 min

Ibutamoren and growth hormone: key differences

Compare stimulation of growth hormone release with hormone replacement, including mechanisms, clinical research, adverse effects and regulatory context.

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